电子邮件：libingxin@zhku.edu.cn

通讯地址：广州市海珠区东沙街24号

教 研 室：基础兽医学教研室

简介：

李冰心，男，1995年2月出生于河南省商丘市，农学博士，讲师，硕士生导师。长期从事中药多糖和非编码RNA调控免疫器官发育相关研究，获得市级及以上课题3项，其中国家自然科学基金1项；以第一作者或通讯作者在《Poultry Science》、《Animals》、《Genomics》、《Genes》、《Acta Biochimica et Biophysica Sinica》、《Biological Trace Element Research》等期刊上发表论文16篇。

教育背景：

（1）2018.09-2021.06   华南农业大学 基础兽医学 博士

（2）2016.09-2018.06   仲恺农业工程学院 兽医 硕士

（3）2012.09-2016.06   仲恺农业工程学院 动物科学（动物医学）学士

工作经历：

2021.10 -至今, 仲恺农业工程学院，讲师

主讲课程：

动物生物化学

研究领域：

兽用中药复方添加剂研发

非编码RNA调控免疫器官发育研究

承担科研项目情况：

国家自然科学基金项目：gga-miR-24-3p通过双靶向CDC20和NOTCH1调控马冈鹅胸腺退化机制研究，2023-2025，主持。

代表性论著：

1. Li Bingxin, Ye Yaqiong, Hong Longsheng, Li Wanyan, Wu Qingru, Liu Wenjun, Ma Yongjiang, Xu Danning, Li Yugu^*. Transcriptome analysis reveals a potential regulatory mechanism of the lnc-5423.6/IGFBP5 axis in the early stages of mouse thymic involution. Acta Biochim Biophys Sin (Shanghai), 2023, 19;55(4):548-560.

2. Sun Zongyi, Li Dejun, Wang Haibin, Ding Yu, Zhang Chun, Wang Shuyue, Wang Xuejiao, Li Bingxin^*, Xu Danning^*. Polysaccharide of Atractylodes macrocephala Koidz (PAMK) protects against DEHP-induced apoptosis in grass carp hepatocytes. Fish & Shellfish Immunology. 2023, 134:108587.

3. Zhang Bingqi, Hong Longsheng, Ke Jingfei, Zhong Yueyun, Cao Nan, Li Wanyan, Xu Dannng, Tian Yunbo, Huang Yunmao, Chen Wenjun, Li Bingxin^*. Polysaccharide of Atractylodes macrocephala Koidz alleviate lipopolysaccharide-induced liver injury in goslings via the p53 and FOXO pathways. Poult Sci, 2023, 102(3):102480.

4. Li Bingxin, Hong Longsheng, Luo Yindan, Zhang Bingqi, Yu Ziyu, Li Wanyan, Cao Nan, Huang Yunmao, Xu Danning, Li Yugu, Tian Yunbo^*. LPS-Induced liver injury of Magang geese through toll-like receptor and MAPK signaling pathway. Animals (Basel), 2022, 13(1):127.

5. Zhou Xiangying, Cao Nan, Xu Danning, Tian Yunbo, Shen Xu, Jiang Danli, Huang Yunmao, Li Wanyan, Li Bingxin^*. Polysaccharide of Atractylodes macrocephala Koidz alleviates cyclophosphamide-induced thymus ferroptosis in gosling. Animals (Basel), 2022, 12(23):3394.

6. Li Bingxin, Li Wanyan, Liu Wenjun, Xing Jingjing, Wu Yingying, Ma Yongjiang, Xu Danning, Li Yugu^*. Comprehensive analysis of lncRNAs, miRNAs and mRNAs related to thymic development and involution in goose. Genomics, 2021, 113(1 Pt 2):1176-1188.

7. Li Bingxin, Zhang Kaizhao, Ye Yaqiong, Xing Jingjing, Wu Yingying, Ma Yongjiang, Li Yugu^*. Effects of castration on miRNA, lncRNA, and mRNA profiles in mice thymus. Genes (Basel), 2020, 11(2):147.

8. Li Bingxin, Li Wanyan, Tian Yunbo, Guo Sixuan, Huang Yunmao, Xu Danning, Cao Nan^*. Polysaccharide of Atractylodes macrocephala Koidz enhances cytokine secretion by stimulating the TLR4-MyD88-NF-κB signaling pathway in the mouse spleen. Journal of Medicinal Food, 2019, 22(9):937-943.

9. Li Bingxin, Li Wanyan, Tian Yunbo, Guo Sixuan, Qian Long, Xu Danning, Cao Nan^*. Selenium-alleviated hepatocyte necrosis and DNA damage in cyclophosphamide-treated geese by mitigating oxidative stress. Biological Trace Element Research, 2020, 193(2):508-516.

10. Li Bingxin, Liu Yang, Li Wanyan, Tian Yunbo, Xu Danning, Cao Nan^*. Effect of selenium on ion profiles and antioxidant defense in mice livers. Biological Trace Element Research, 2018, 184(1):127-135.